(Click for larger image)

Mukherjee, Siddhartha. THE GENE: AN INTIMATE HISTORY. New York City, NY: Scribner, 2016. Hardcover. First Edition/First Printing. 595 pages. Fine/Fine.

Book-length account on subject. One of the definitive books on its subject for our time. The First Hardcover Edition. Precedes and should not be confused with all other subsequent editions. Published in a small and limited first print run as a hardcover original only. Presents Siddhartha Murkherjee's "The Gene: An Intimate History". His second book, another magisterial account, this time on genetics. It is intimately linked with his ground-breaking book on cancer because the latter is fundamentally genetic in nature, hence complex and intractable. "Just as informative, wise, and well-written. Opens with a survey of how the gene first came to be conceptualized and understood, taking us through the thoughts of Aristotle, Darwin, Mendel, Thomas Morgan, and others. He finishes the section with a look at the case of Carrie Buck (to whom the book is dedicated), who eventually was sterilized in 1927 in a famous American eugenics case. Buck's sterilization comes as a warning that informs the rest of the book: This is what can happen when we start tinkering with this most personal science and misunderstand the ethical implications of those tinkerings. Illustrates how the science has grown so much more advanced and complicated since the 1920's: We are developing the capacity to directly manipulate the human genome, and how the ethical questions have also grown much more complicated. We could ask for no wiser, more fascinating, and talented writer to guide us into the future of our human heredity" (Chris Schluep). "Perhaps the greatest detective story ever told. A millennia-long search, led by a thousand explorers, from Aristotle to Mendel to Francis Collins, for the question marks at the center of every living cell. Prodigious, sweeping, and ultimately transcendent. If you're interested in what it means to be human, today and in the tomorrows to come, you must read this book" (Anthony Doerr). An absolute "must-have" title for Siddhartha Mukherjee collectors. This copy is very prominently and beautifully signed in black pen-marker on the title page by Siddhartha Mukherjee. It is signed directly on the page itself, not on a tipped-in page. Mukherjee's specimen-signature on this copy is one of the best we have ever seen: Big, bold, and elegant. Laid-in is a pristine copy of the Souvenir Material of the event during which his signature was obtained. This title will become a contemporary classic. This is one of very few such signed copies of the First Hardcover Edition/First Printing still available online and is in especially fine condition: Clean, crisp, and bright, a pristine beauty. A rare signed copy thus. Winner of the Pulitzer Prize for Non-Fiction in 2011 for "Emperor of All Maladies: A Biography of Cancer". One of the most brilliant American writers of our time. A fine copy. (SEE ALSO OTHER SIDDHARTHA MUKHERJEE TITLE IN OUR CATALOG). ISBN 1476733503. $100.00

This item is available for purchase. This web page was most recently updated on February 27, 2017.